October 4, 2022
Welcome to the latest edition of the VINEx Grapevine.

If you have any feedback or would like to share any publications or articles we may have missed, please send them to:

If you wish to opt out, simply click on the “unsubscribe” button.

Inez Jabalpurwala
Global Director - VINEx


Bienvenue à la dernière édition de "La vigne" de VINEx.

Si vous avez des commentaires, ou si vous souhaitez nous faire part de publications ou d'articles qui nous ont échappée, veuillez les envoyer par courriel à :

Si vous souhaitez vous désabonner, il vous suffit de cliquer sur le bouton "désabonnement".

Inez Jabalpurwala
Directrice mondiale - VINEx

VINEx in the news
VINEx was one of the Canadian organizations selected to participate in the World Health Organization’s public hearings on pandemic preparedness. You can watch VINEX’s submission in relation to a new international instrument on pandemic prevention, preparedness and response (the 1h20min mark in the second round of public hearings on day 2) and/or read it below:

"One of the unexpected consequences of the COVID-19 pandemic was the emergence of a post COVID-19 condition, as defined by WHO, more commonly known as Long COVID. Long COVID is having devastating impacts on health, society and the economy—it is estimated that anywhere from 10 to 30 percent of people infected by the virus are living with Long COVID. While there are as many as 200 reported symptoms, many of the most frequently reported are neurological or psychiatric, and these symptoms persist. Yet, for those with Long COVID, potentially up to 190 million people worldwide based on confirmed COVID-19 infections as of September 9th, there are limited answers and care options.
The COVID-19 pandemic was unprecedented. However, there are precedents of viral pandemics leading to neurological and psychiatric illness going back centuries; and there will be more, especially as the climate changes, human built-environments expand, and animal-human interactions increase.
We must build investments to advance our understanding of post-viral conditions (including Long COVID), and measures to develop care and treatment options, into pandemic preparedness. In addition, as the COVID-19 pandemic’s impact on brain health illustrates, there is a need to have a better understanding of the intersection of brain health and the physical environment. This will be key for pandemic preparedness and response. If and when a future pandemic impacts brain health, we need pathways to possible solutions that could be rapidly scaled and deployed."
COVID-19 and the brain
McGill to launch Quebec-wide study on Long COVID
VINEx approached Quebec’s Chief Scientist to expand the clinical trial led by Dr. Emilia Falcone, to include a cognitive assessment. We are pleased to see this work now underway, let by Dr. Lesley Fellows.
The Ontario COVID-19 Science Advisory Table has published a informative brief on Long COVID: “Understanding the Post COVID-19 Condition (Long COVID) in Adults and the Expected Burden for Ontario”. Recommendations include “a proactive and comprehensive strategy to manage the post COVID-19 condition needs to be developed by health systems and policy makers. This strategy should include substantial investments in research and health system resources to mitigate the long-term health, social, and economic impacts of the post COVID-19 condition in Ontario."
At least 17 million people in the WHO European Region experienced long COVID in the first two years of the pandemic; millions may have to live with it for years to come. The World Health Organization looks at the incidence and impact of Long COVID in Europe. “While there is much we still need to learn about long COVID, especially how it presents in vaccinated versus unvaccinated populations and how it impacts reinfections, this data highlights the urgent need for more analysis, more investment, more support, and more solidarity with those who experience this condition,” said Dr. Hans Henri P. Kluge, WHO Regional Director for Europe.
More Long COVID coverage:

Harvard Magazine - The Causes of Long COVID
British Medical Journal - How “long covid” is shedding light on postviral syndromes
Science News - Who has the highest risk of long COVID? It’s complicated
Time - Long COVID Experts and Advocates Say the Government Is Ignoring 'the Greatest Mass-Disabling Event in Human History'
British Medical Journal - The needs of patients with Long COVID must not be ignored
Scientific Articles:

Nature Medicine - Long-term neurologic outcomes of COVID-19. The authors show that "... beyond the first 30 days of infection, people with COVID-19 are at increased risk of an array of neurologic disorders spanning several disease categories including stroke (both ischemic and hemorrhagic), cognition and memory disorders, peripheral nervous system disorders, episodic disorders, extrapyramidal and movement disorders, mental health disorders, musculoskeletal disorders, sensory disorders and other disorders including Guillain–Barré syndrome, and encephalitis or encephalopathy. Read more about the findings in The Tyee and from the Washington University School of Medicine.

Journal of Alzheimer's DiseaseAssociation of COVID-19 with New-Onset Alzheimer’s Disease. In this retrospective cohort study of people with COVID-19,  there results showed a  significantly increased risk of Alzheimer’s disease a year after initial COVID-19 diagnosis  especially in people over 85 years old and in women. Read a summary of the findings in New Atlas.
Pandemic Preparedness
After the pandemic — Canada must boost research funding to safeguard our future health
McGill Professor Abraham Fuks and Senator Stan Kutcher co-authored an op-ed in the Ottawa Citizen calling for increased investment health research funding in order to be prepared for future health threats.
In Memoriam
Everyone involved with VINEx was deeply saddened to learn of the passing of Dr. Pierre Talbot, a world-renowned virologist whose work spanning a career advanced our understanding of how viruses impact the human system. He so generously gave his time and insights as VINEx was taking form early in the pandemic, as a Special Advisor on our Science Advisory Council. We extend our heartfelt condolences to his family, and to his many colleagues and collaborators.

Toutes les personnes travaillant avec VINEx ont été profondément attristées d’apprendre le décès du professeur Pierre Talbot, un virologue de renommée mondiale dont les travaux, tout au long de sa carrière, ont fait progresser notre compréhension de l’impact des virus sur le corps humain. Il a si généreusement donné de son temps et ses idées alors que VINEx prenait forme au début de la pandémie, en tant que conseiller spécial au sein de notre Conseil consultatif scientifique. Nous présentons nos sincères condoléances à sa famille, ainsi qu’à ses nombreux collègues et collaborateurs.

Visit our website and follow us on social media to stay up to date on the latest evidence-based news and publications on viruses and the brain
Copyright © 2022 VINEx, All rights reserved.