October 08, 2019
Giving healthcare companies the exposure they deserve. Every Tuesday.
BioTuesdays by Kilmer Lucas


OncoSec TAVO technology aiming to reverse checkpoint inhibitor resistance

OncoSec Medical (NASDAQ:ONCS) is developing its TAVO drug candidate to enhance local delivery and uptake of DNA-based interleukin-12 (IL-12) directly into solid tumors to reverse patients’ resistance to checkpoint inhibitors.

“As successful as checkpoint inhibitors are, anywhere from 60% to 90% of patients with solid tumors don’t respond to drugs such as Merck’s KEYTRUDA,” Daniel O’Connor, president and CEO, says in an interview with BioTuesdays. 

Checkpoint inhibitors are a widely used form of cancer immunotherapy that stimulate the body’s own immune response. Some cancer cells make high levels of proteins that can halt the immune system, disrupting the ability of T-cells to attack cancer cells. Checkpoint inhibitors turn the immune system back on so T-cells are able to recognize and kill cancer cells.
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Presents novel NSCLC study design for plinabulin


Hepion Pharmaceuticals

Promotes Daren Ure, Daniel Trepanier and Patrick Mayo to management team



Enrolls first patient in U.S. multi-center trial in dry AMD


Ra Pharmaceuticals

Doses first patient in pivotal Phase 3 myasthenia gravis study

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About BioTuesdays

BioTuesdays was created in 2009 by Kilmer Lucas, a leading healthcare-only investor relations firm. Employing a unique "outsourced in-house" partnership model, Kilmer Lucas designs and executes customized IR & PR programs for its drug development, medical device, cell therapy, diagnostics and healthcare services clients. But, most of BioTuesdays' content isn't client-driven. Rather, our mission is to give as many great healthcare companies and their stories as much exposure as we can.
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