September 10, 2019
Giving healthcare companies the exposure they deserve. Every Tuesday.
BioTuesdays by Kilmer Lucas


DelMar Pharma developing VAL-083 in biomarker-driven GBM patient populations

DelMar Pharmaceuticals (NASDAQ:DMPI) is conducting two Phase 2 clinical trials with its lead drug candidate, VAL-083, a DNA-targeting agent, in three distinct biomarker-driven glioblastoma multiforme (GMB) patient populations.

“Previous work at the NCI and additional data from our own studies have demonstrated that VAL-083 crosses the blood-brain barrier, has biological and tumor effecting activity against a range of cancers, including GBM and ovarian and resulted in a safety database of more than 1,000 patients,” Saiid Zarrabian, president and CEO of DelMar, says in an interview with BioTuesdays.

“Effectively, we are in two highly de-risked late-stage Phase 2 programs, targeting MGMT-unmethylated GBM tumors, which more than 60% of GBM patients have,” he adds. Methylguanine DNA-methyltransferase (MGMT) is a DNA repair enzyme.
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About BioTuesdays

BioTuesdays was created in 2009 by Kilmer Lucas, a leading healthcare-only investor relations firm. Employing a unique "outsourced in-house" partnership model, Kilmer Lucas designs and executes customized IR & PR programs for its drug development, medical device, cell therapy, diagnostics and healthcare services clients. But, most of BioTuesdays' content isn't client-driven. Rather, our mission is to give as many great healthcare companies and their stories as much exposure as we can.
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