SFARI is pleased to announce that it has selected six finalists in response to the Bridge to Independence Award request for applications. This new awards program is intended to invest in the next generation of top autism investigators by identifying talented early-career scientists and facilitating their transition to an independent research career.
Whole-exome sequencing and associated phenotypic data from the Simons Simplex Collection (SSC) are now accessible online via a cloud-based database hosted by WuXi NextCODE in partnership with SFARI. SSC data may also be analyzed alongside other datasets to confirm new discoveries and clinical diagnoses related to autism spectrum disorders. Researchers can apply for training and access to the WuXi NextCODE SSC portal here.
Recently published findings from SFARI-funded investigators include: a role for the maternal interleukin-17A pathway in autism; adult reversal of select autism-like phenotypes in SHANK3 mutant mice; and CRISPR-engineered models of human microdeletion/duplication syndromes. Brief summaries of these studies can be found here.
A complete list of SFARI-funded publications is available here.
The burgeoning research field known as the fetal origins of adult disease (FOAD), or the developmental origins of health and disease, demonstrates that maternal distress during pregnancy affects fetal and infant brain-behavior development. Catherine Monk will describe her lab's FOAD studies that focus on women in the perinatal period and fetal and infant neurobehavioral development, including direct studies of the fetus, newborn brain imaging and placental methylation.
Wednesday, March 30, 2016
The mission of the Simons Foundation Autism Research Initiative (SFARI) is to improve the understanding, diagnosis and treatment of autism spectrum disorders by funding innovative research of the highest quality and relevance.