Blockchain goes to the bank. What are neoantigens? The future of enterprise IT.

That escalated quickly

Hi there,

This is such a good newsletter subject line idea.

You’ve been warned.

Break the bank

As blockchain and decentralized ledger technology evolve, the traditional banking industry will need to adapt — or risk being replaced.

From payments to fundraising to loans and credit, we examine how blockchain could disrupt banking.

The VC game is crazy

VC extraordinaire, Fred Wilson, recently penned a post about what happens when a founder is fully vested (see The Blurb).  

As a company that raised late in its life, this part was crazy to me.

It highlights a few interesting things:

  • VCs quickly become the boss. Founders are employees.

  • Founder & new outside CEO seem pretty fungible.

  • The game is short- to medium-term (not a long game).

So trendy

In our newest NExTT report, we take a look at what 2019 has in store for enterprise IT.

From quantum computing to machine learning for businesses to serverless tech, check out all 16 trends to watch here.

 Not your father's cardboard

With pressure from corporate shareholders and shifting consumer preferences, the packaging landscape is changing rapidly.

From eco-friendly packaging to interactive labels to self life extension, we've mapped out 45+ startups driving innovation in the space. Expert Intelligence clients can see them all here.

The long game

From Farnam Street, there is a great post in The Blurb about the power of playing the long game. I liked this part below.

New plan

Many current cancer treatments are unable to consistently and reliably target cancer cells.

Now scientists are working with neoantigens, proteins found specifically on cancer cells, to develop personalized vaccines for more targeted, consistent cancer treatment. 

We break down the vaccine process, companies working with the technology, and more. Check it out here.

 Money, money, money

With consumer and business preferences shifting away from paper cash and checks, public and private companies are working to develop payment methods for the 21st century.

Private payment tech companies have raised $30B+ since 2014. We dig into where that money is being deployed and where the payment sector is headed. Clients can read about it here.

Long-term greedy

Eric Paley penned a post about when venture capital becomes vanity capital. It’s in The Blurb and talks about why raising less capital or raising capital later is better.

It’s antithetical to the whole ethos of investors foie gras’ing startups that is going on now which we discussed in this podcast.

He compares Zappos vs. Wayfair. Zappos is a poster child for VC-backed businesses. The Wayfair founders raised late and cleaned up.

The Industry Standard

CB Insights data is the most trusted by those in the industry and the media. A few recent hits.

Bloomberg. Yoolim Lee (@yoolimleenews) reports that SoftBank Vision Fund and Alibaba led a $1.1B investment in Tokopedia and references CB Insights data.

Entrepreneur. Frank Roessler (@frank_roessler) gives advice on how to be a successful entrepreneur and cites CB Insights research.

Xconomy. Brian Dowling (@be_d) reports that Hubspot is launching a $30M corporate venture capital fund and refers to CB Insights research.

I love you.


P.S. Tomorrow we're discussing advanced manufacturing trends to watch in 2019. If you haven't already, sign up for the briefing here.

The Blurb

A curated mix of articles worth sharing.

Wear the vest. Fred Wilson discusses what happens when a founder is fully vested.

Go long. Big successes are often the result of a series of smaller, strategic steps.
Farnam Street

You’re so vain. At what point does venture capital become vanity capital?

I need this now. The two-week pay cycle may be making the lives of workers of all income levels more difficult.

I know who you are. Researchers found that anonymized data can be easily “reidentified.”
Fast Company

See you in court. Sidecar is suing Uber for alleged "predatory pricing and anticompetitive practices" that put it out of business.
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